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Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.

The document's conclusion cannot be provided because the document is not accessible or understandable.

Dermal adipose tissue in mice can change and revert to help with skin health.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Certain medications can impact metabolic syndrome, with some improving conditions like high blood sugar and others having no effect.

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.

Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).

Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.

Targeting lipid metabolism can help treat advanced, resistant cancers.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

There are many ways to treat Polycystic Ovary Syndrome, including lifestyle changes, surgery, and various medications, but more research is needed for better treatments.

Balding people may have higher heart disease risk.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Fish oil improves skin health in people with diabetes and high cholesterol.

ADAM17 could be a potential target for treating PCOS.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.

Different types of skin cells play specific roles in development, healing, and cancer.

Fat cells in the skin help start healing and form important repair cells after injury.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.