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In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.

This study found that the enzyme Acer1 plays a crucial role in skin health and tumor prevention by regulating ceramide metabolism in mice.

In this study, researchers found that male and female APCHi mice exposed to ionizing radiation showed near-normal lipid and metabolite levels, suggesting activated protein C may offer some protective effects against radiation-induced damage affecting organ systems.

This study observed that treating acne scars with fractional ablative laser concurrently with isotretinoin improved outcomes more effectively compared to applying the laser 6 months after isotretinoin treatment ended, as measured by the Quantitative Global Acne Scarring Grading System.

This study investigated autophagy activator ICP5249 and found it promotes hair growth by enhancing cell proliferation and autophagy-related markers in human dermal papilla cells and hair follicles, with AMPKα playing a regulatory role, suggesting its potential as a hair growth ingredient.

In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.

This study found that N-acetyl cysteine and metformin had equal effects on clinical outcomes in anovulatory infertile women with PCOS, but NAC was better tolerated with fewer side effects.

This study found that a new peptide, Snakin-Z, from Ziziphus jujuba fruits, shows significant inhibitory effects on AChE and BChE enzymes and strong antioxidant activity, suggesting potential benefits for Alzheimer's disease treatment.

This review covers the current status of the interstitial pneumonia with autoimmune features (IPAF) category, pointing out the need for revision of its criteria to establish it as a standalone diagnostic term, but reports no new clinical findings.

In this case-control study, researchers found that serum apelin-12 levels were significantly higher in acne patients and correlated with acne severity, BMI, insulin resistance, and inflammation, suggesting that managing insulin resistance could be important for acne treatment.

This article reviews the regulation and roles of spermidine/spermine-N(1)-acetyltransferase (SSAT) in polyamine metabolism and its potential as a target in cancer and other diseases, without reporting new experimental results.

In this case report, two female patients with refractory systemic lupus erythematosus showed significant improvement after treatment with the JAK inhibitor upadacitinib, indicating potential as a promising option for difficult cases, although further research is needed to confirm its broader safety and efficacy.

This study's simulation found that Ascorbyl Tetraisopalmitate penetrates more efficiently through the skin's stratum corneum than via the infundibulum, following different pathways and dynamics in each membrane.

This review discusses guidelines for acitretin use in dermatology, reporting its efficacy in severe psoriasis and recommendations for combination therapies, without providing new clinical trial results.

This report describes a case of HAIR-AN syndrome in a young woman, characterized by acanthosis nigricans, insulin resistance, and polycystic ovaries, highlighting its rarity and multisystem nature.

This case report highlights significant improvement in a patient with severe alopecia areata who responded well to ivarmacitinib after a suboptimal response to another JAK inhibitor, tofacitinib, suggesting ivarmacitinib as a potential alternative for tofacitinib-refractory cases.

This case study suggests a potential connection between insulin resistance-induced diabetes and the development of migraine symptoms in a patient with HAIR-AN syndrome, highlighting the importance of early diagnosis and a multifaceted treatment approach.

Acanthosis Nigricans is the most common skin sign of insulin resistance.

This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.

This randomized clinical trial found that adjunctive apple cider vinegar supplementation significantly improved the resolution of metabolic syndrome, reduced insulin resistance, and enhanced quality of life and sexual function in women with PCOS and metabolic syndrome, compared to a placebo group.

This review discusses consensus guidelines for the use of acitretin in psoriasis, highlighting its ongoing utility in both mono and combination therapies, despite not always being recognized in treatment guidelines.

This study found that fractional infrared technology may improve skin laxity and thickness in the cervical area without side effects in a small group of patients.

In this quasi-experimental study, a 12-week intermittent fasting regimen significantly improved insulin sensitivity and reduced HbA1c levels in overweight South Asian adults with prediabetes, suggesting a practical lifestyle strategy to potentially delay the onset of type 2 diabetes.

This study concluded that acanthosis nigricans in female adolescents with PCOS is a marker of obesity but not an indicator of insulin resistance or glucose intolerance.

This study found that transcutaneous electrical acustimulation aided wound healing in mice by enhancing expression of proteins related to signaling pathways, stress recovery, and mitochondrial function.

In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.

In this case report, a 3-year-old male with IFAP syndrome showed moderate improvement in skin symptoms and corneal erosions but no change in alopecia or photophobia after 6 months of acitretin therapy.

This study found that over 80% of women treated with paclitaxel who used a hypothermic glycerin-based hydrogel cap preserved at least 50% of their initial hair volume, suggesting scalp cooling may effectively prevent chemotherapy-induced alopecia.

This case report details a rare instance of primary adrenal insufficiency as a manifestation of antiphospholipid syndrome, with the patient successfully managed through glucocorticoids, warfarin, and hydroxychloroquine.