TLDR Acitretin moderately improved skin and eye issues but not hair loss or light sensitivity in a 3-year-old with IFAP syndrome.
A 3-year-old male patient with ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome exhibited cutaneous and ocular symptoms from infancy, along with growth retardation and borderline intelligence, but no other systemic issues. Treatment with acitretin (1 mg/kg) for 6 months resulted in moderate improvement in skin conditions and corneal erosions, though there was no change in alopecia or photophobia.
75 citations,
September 1985 in “Archives of dermatology” Two boys had a rare skin condition needing to be differentiated from similar disorders, with unclear inheritance due to few cases.
The document describes a rare case of IFAP syndrome, a genetic condition with symptoms of hair loss, light sensitivity, and scaly skin.
June 2017 in “Journal of Clinical and Health Sciences” A woman developed folliculitis after long-term acitretin treatment for pustular psoriasis.
A woman developed folliculitis after taking acitretin for psoriasis, which was treated with skin dressing and antibiotics.
40 citations,
August 2005 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Acitretin moderately improved skin and eye issues but not hair loss or light sensitivity in a 3-year-old with IFAP syndrome.
