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Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Women with acne have lower levels of a specific hormone marker than women without acne.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

Interest in acne is rising, but research funding has significantly decreased.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Excessive androgen in women can cause acne, hair growth, baldness, and PCOS, often treatable with medication.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

People with severe acne tend to have higher levels of betatrophin.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Higher androgen levels do not cause baldness in men.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Adipokines affect skin health and could be targeted for treating skin diseases.

Baricitinib is effective for treating severe alopecia areata in Japanese patients, but long-term safety needs more study.

Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.