June 2021 in “International journal of research in dermatology” This report describes a child and his father with hereditary hypotrichosis simplex, an uncommon isolated form of hair loss, with no other ectodermal or systemic abnormalities noted.
January 2021 in “International journal of pharmaceutical research” In this study, the researchers found that the ethyl acetate fraction of Sansevieria trifasciata P. (20%) was just as effective as minoxidil (2%) in promoting hair growth in male rabbits, with notable results in hair follicle proliferation and a favorable anagen to telogen ratio.
January 2021 in “Figshare” This study found that autophagy in the preputial glands of mice plays a crucial role in regulating lipid and fatty acid metabolism, as well as pheromone production.
This study found that a single 8Gy dose of superficial 50kV X-ray radiation minimizes keloid recurrence after excision, and identified genomic pathways and potential molecular targets for improved keloid therapy.
June 2020 in “Research Square (Research Square)” This study found that oral contraceptives containing cyproterone acetate significantly improved the overall quality of life in polycystic ovary syndrome patients after six months, compared to those containing levonorgestrel.
April 2020 in “Research Square (Research Square)” This study found that oral contraceptives containing cyproterone acetate improved the overall quality of life in PCOS patients more than those containing levonorgestrel after 6 months of treatment.
March 2020 in “QJM: An International Journal of Medicine” This study found that intradermal minoxidil 5% alone and with intralesional triamcinolone acetonide significantly reduced alopecia areata dermoscopic findings, while standard intralesional corticosteroids remain the main first-line treatment for patchy alopecia with less than 50% scalp involvement.
January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology” This study found that minoxidil increases trabecular meshwork cell permeability, possibly via the downregulation of tight junction proteins and the generation of reactive oxygen species.
December 2019 in “Orvostudományi Értesítö” This article reviews treatment approaches for polycystic ovary syndrome, highlighting lifestyle changes, medications like metformin for insulin resistance, and fertility therapies, acknowledging the complexities and contraindications involved.
August 2019 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” This review discusses the pathophysiological characteristics and treatment options for polycystic ovary syndrome, reporting no new clinical results; the authors emphasize combining non-pharmacological measures with pharmacological treatments for optimal patient management.
August 2019 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” This review discusses the pathophysiology of polycystic ovary syndrome and its non-pharmacological and pharmacological treatment options, but reports no new clinical results.
July 2019 in “Majalah Obat Tradisional” This study reported that a 4% water fraction of green tea leaf extract showed the most effective hair growth promotion in rabbits.
This study found that ethanolic extract and fractions of Ceiba leaf tonic may enhance rabbit hair growth similarly to 2% minoxidil.
April 2018 in “Journal of Investigative Dermatology” This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.
April 2018 in “International journal of innovative research in medical science” In this randomized controlled clinical study, researchers found that Neem and Zanjabeel treatment was as effective as standard hormonal therapy in reducing hirsutism and improving biochemical and hormonal parameters in women with polycystic ovarian disease, while also significantly lowering fasting insulin and lipid levels.
January 2018 in “Urologe A” In this case report, botulinum neurotoxin injections were associated with a 6-month cessation of priapism episodes in a young man with recurring low-flow priapism, following unsuccessful conventional treatments.
In this case report, combination therapy with topical tretinoin, topical and intralesional steroids, and systemic doxycycline showed improvement in AKN lesions for a 19-year-old man, with notable reductions in lesion size and number observed by the second week.
October 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This study suggests that PGD2 may increase testosterone production in keratinocytes through oxidative stress pathways, with n-acetyl-cysteine blocking this effect.
July 2017 in “Journal of Young Pharmacists” In this study, the ethyl acetate fraction of Nothopanax scutellarium leaves showed a mild irritation effect but promoted hair growth and increased hair diameter in rabbits.
May 2017 in “InTech eBooks” This review discusses trichotillomania and traction alopecia, focusing on their clinical features, diagnostic criteria, and treatment options, but it reports no new research findings.
April 2017 in “Journal of Pharmaceutical Investigation” In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.
This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.
September 2016 in “Journal of Dermatology and Dermatologic Surgery” This case report describes a rare instance where scalp psoriasis mimicked severe alopecia, initially misdiagnosed as central centrifugal cicatricial alopecia.
April 2016 in “Journal of the American Academy of Dermatology” Incorrect injection of corticosteroids for alopecia areata can cause skin problems.
April 2016 in “Journal of Investigative Dermatology” This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.
April 2016 in “Journal of Investigative Dermatology” This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
April 2016 in “Apollo (University of Cambridge)” This article reviews treatment approaches for trichotillomania, emphasizing differences from OCD therapies and recommending specific management strategies, without providing new experimental findings.
January 2016 in “Case reports in clinical medicine” This article discusses monilethrix in a 6-year-old girl, explores various aspects of the disease, and its treatment, but reports no new clinical results.
January 2016 in “Springer eBooks” This article reviews causes and treatments of hyperandrogenism, including hirsutism and acne, but presents no new clinical findings.
September 2015 in “Journal watch” Triamcinolone acetonide injections help regrow hair in alopecia areata patients.