3 citations,
October 2003 in “Annals of Oncology” A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.
1 citations,
September 2018 in “International journal of research - granthaalayah” Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.
March 2023 in “Clinical, cosmetic and investigational dermatology” IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
14 citations,
March 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
3 citations,
September 2019 in “Clinical and experimental dermatology” Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
July 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
180 citations,
January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is crucial for normal skin and hair growth.
21 citations,
July 2014 in “British Journal of Dermatology” Hair thickness matters more than density for baldness in Japanese men over 25.
1 citations,
January 2011 in “Journal of S C C J” Adenosine lotion improves hair thickness and density in women with thinning hair.
January 1999 in “Journal of S C C J” Certain growth factors regulate hair growth cycles, male hormones affect hair cycles, and drugs like Minoxidil and Finasteride can stimulate hair growth and inhibit male pattern baldness respectively.
40 citations,
September 2012 in “European Journal of Dermatology” Laser hair removal significantly improves acne keloidalis nuchae, especially with early treatment.
13 citations,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
4 citations,
March 2014 in “The FASEB Journal” The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
22 citations,
December 2013 in “Molecular biology of the cell” ILK is essential for proper hair follicle development and structure.
7 citations,
November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.
May 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
1 citations,
October 2022 in “Biomedicines” Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
20 citations,
October 2017 in “Stem Cell Reports” Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
41 citations,
June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
1 citations,
September 2023 in “Life science alliance” Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.
107 citations,
June 1997 in “PubMed” EGFR is essential for normal hair development and follicle differentiation.
66 citations,
November 2011 in “Journal of The American Academy of Dermatology” A handheld dermatoscope helps diagnose different types of hair loss effectively.
179 citations,
June 2000 in “The American journal of pathology” The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.
67 citations,
May 2010 in “Journal of The American Academy of Dermatology” Some chemotherapy can cause permanent hair loss.
36 citations,
May 2015 in “Australasian Journal of Dermatology” Low dose oral minoxidil helps regrow hair in permanent chemotherapy-induced alopecia.
8 citations,
February 2017 in “Archives of Dermatological Research” Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.
8 citations,
January 2007 in “International journal of experimental pathology” Hairless HRS/J mice resist Bacillus anthracis skin infections due to high numbers of immune cells, not because they lack hair follicles.