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This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.

This research reports a new autosomal recessive mutation in mice, 'lanceolate hair', causing generalized alopecia and hair shaft abnormalities, which may serve as a model for Netherton's syndrome in humans.

This study found that a nonsense mutation in the Cst6 gene of mice leads to severe skin and hair abnormalities, suggesting that cystatin M/E is crucial for epidermal function and viability.

This review discusses the cornification process of epidermal keratinocytes in forming the skin barrier and reports no new results; it emphasizes the importance for diagnosis and treatment of skin disorders.

This source discusses ichthyosis, a disorder causing dry, scaly skin, by exploring its genetic causes, potential systemic associations, and treatments, and correlates modern medical insights with Unani medicine principles focused on humoral balance and holistic care.

This study found that lipid and acne inhibitive cream improved the skin condition in a rabbit ear acne model, showing significant changes in follicular cornification.

This study found that Compound Diandao Pulvis Drug Facial Mask improved some signs of acne in a rabbit ear model, but its effects were not significantly different from tretinoin cream.

This study found that resolving acne capsules may suppress acne keratosis and regulate hormone levels in a rabbit ear acne model, showing potential anti-acne effects.

This study identified biallelic variants in the LSS gene as a possible genetic cause of palmoplantar keratoderma-congenital alopecia syndrome type 2, highlighting the role of cholesterol synthesis in skin cornification.

Norfolk Terriers have a genetic skin defect causing scaling and blisters due to a keratin issue.

This study found that keratin filament networks in SG1 cells of mice undergo dynamic changes during cornification, impacting the barrier function of the stratum corneum.

This review outlines a diagnostic framework for clinicians to distinguish different types of inherited ichthyoses and suggests further testing and treatment strategies, but reports no new clinical results.

This review explores theories on the evolution of hair from synapsid scales and glands, proposing mechanisms supported by comparative studies, but reports no new experimental findings.

This study found that transgenic expression of COX-2 in mouse basal keratinocytes causes epidermal hyperplasia and certain dysplastic features at specific body sites.

This study found that Super Merino sheep have a higher wool follicle density, finer fleece, and distinct gene expression compared to Small Tail Han sheep, which may inform future breeding and genetic interventions.

This review discusses the genetic disorder, monilethrix, characterized by fragile, brittle hair and its inheritance patterns, and reports no new clinical results.

This chapter reviews various skin disorders classified as Mendelian disorders of cornification and reports no new clinical findings, highlighting the complexity of genetics involved in inherited ichthyoses.

This review examines the process of cornification as a mode of programmed cell death and outlines how keratinocytes activate anti-cell death mechanisms to maintain epidermal homeostasis, but reports no new results.

This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.

This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.

This article discusses Ayurvedic perspectives on acne vulgaris and outlines potential natural remedies, but it presents no new clinical findings.

This study demonstrated that in genetic mouse models, the calcium sensor Stim1, not Stim2, is essential for sweat secretion in sweat glands.

This study found that WWOX deficiency in mice leads to impaired skin development, reduced epidermal thickness, and significant hypothermia due to disrupted cell proliferation and homeostasis.

Cathepsin L deficiency causes hair and skin issues in mice.

Balanced protease activity is crucial for healthy skin and hair development.

This review discusses the mechanisms of skin-associated cell death and their potential role in treating inflammatory skin diseases, but presents no new clinical findings.

This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.

This abstract describes the processes for recognizing foreign medical degrees in the US and the reciprocal credentialing of US medical qualifications in Poland, highlighting differences in evaluation and certification requirements between the two countries.

This review discusses the role of epithelial–mesenchymal transition in cutaneous fibrotic disorders and highlights potential molecular targets for therapy, but reports no new clinical results.

This study found that lysine carboxymethyl cysteinate helps protect the epidermis from UVB-induced damage by activating autophagy and restoring cornification processes in a skin model.