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Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Both drugs lower DHT levels, with GI198745 being more effective.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Scalp cooling significantly reduces hair loss in chemotherapy patients.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Certain drugs that block specific enzymes can help treat prostate diseases.

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.