Scalp Cooling in the Prevention of Anthracycline-Induced Alopecia

    April 2001 in “ European journal of cancer ”
    Éric Lenaerts, M. Meyen, Tamara Maes, Hannelore Maes, A. El Mousati, J.A.M. Lemmens, Luc Dirix, P. Huget
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    TLDR Scalp cooling prevented hair loss in half of the patients, despite significant side effects.
    The study investigated the effectiveness of scalp cooling in preventing anthracycline-induced alopecia in 29 early breast cancer patients undergoing chemotherapy. Using the PinguinR scalp cooling system, 51% of patients still developed alopecia, resulting in a 50% success rate for the cooling method. Despite side effects such as pain, headache, dizziness, nausea, and vomiting, 70% of patients favored the treatment. The study concluded that while scalp cooling was effective for half of the patients, the side effects were significant, yet the overall patient appraisal was positive.
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