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The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride helps protect brain in old male rats.

Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

Forensic hair analysis for drugs is now more reliable and accurate.

The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Vegetarians should take B vitamin supplements to avoid health issues.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.

Understanding hair follicles through various models can help develop new treatments for hair disorders.

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

The compounds tested could potentially treat hair loss and alopecia.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.