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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Finasteride 5 mg effectively reduces urinary symptoms and PSA levels in men with enlarged prostates, with few sexual side effects.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Rats had lasting erectile problems after stopping a certain medication.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

5% minoxidil foam is a safe, effective treatment for male pattern hair loss, with increased hair count and few side effects.

The document concludes that various treatments for skin conditions are effective, but some require further research, and certain factors like gender and lifestyle can influence disease outcomes.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Finasteride temporarily lowers male rat fertility without affecting libido.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Both drugs lower DHT levels, with GI198745 being more effective.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Most women with hair loss using 5% topical Minoxidil are satisfied with the treatment, but hair loss still affects their daily habits and social life.

More frequent and severe skin problems are linked to higher daily alcohol consumption.

Finasteride safely lowers DHT levels without affecting testosterone.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.

Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.