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The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Two people lost hair unexpectedly after getting a common hair loss treatment with a drug called Dutasteride.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Dutasteride is more efficient than finasteride, but individual results vary.

Androgenic alopecia is mainly caused by DHT, and new treatments focus on hair regeneration and aging factors.

The higher dose supplement was more effective in treating female hair loss.

Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Certain drugs that block specific enzymes can help treat prostate diseases.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.