Comparative Study of Two Dietary Supplements Inhibiting 5α-Reductase in Female Androgenetic Alopecia

The document details a study comparing the effectiveness of two dietary supplements inhibiting the 5α-reductase enzyme in treating female androgenetic alopecia (FAA) in 60 postmenopausal women. The first supplement, with higher doses of Pygeum africanum/Serenoa repens (100 mg each) and MSM (500 mg), significantly improved hair count, the proportion of anagen phase hairs, and hair resistance to traction after 16 weeks, compared to the second supplement with lower doses (50 mg each) and a placebo group. The study concluded that the higher dose supplement, named Complidermol 5a PLUS, was more effective in treating FAA, showing a "PLUS effect" in clinical outcomes and patient satisfaction, suggesting it could improve long-term treatment adherence.