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research Risk of Age-Related Macular Degeneration in Men Receiving 5α-Reductase Inhibitors: A Population-Based Cohort Study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
![Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
research MRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia
Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
research Comparative Clinical Study Evaluating the Efficacy and Safety of Topical 5% Cetosomal Minoxidil and Topical 5% Alcohol-Based Minoxidil Solutions for the Treatment of Androgenetic Alopecia in Indian Men
Cetosomal minoxidil is safer and as effective as alcohol-based minoxidil for male hair loss treatment.
research Hair And Nail Disorders In Children With Fitzpatrick Skin Type V
Children with darker skin can have various hair and nail issues.
research Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats
Pueraria mirifica extract may help treat benign prostatic hyperplasia.
research Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family
A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.
research Comparative Efficacy of Topical Finasteride (0.25%) in Combination With Minoxidil (5%) Against 5% Minoxidil or 0.25% Finasteride Alone in Male Androgenetic Alopecia: A Pilot, Randomized Open-Label Study
Using both minoxidil and finasteride together is more effective for male hair loss than using either one alone.
research Persistent Virilization and Vasomotor Symptoms in a Transman 5 Years Post Testosterone Withdrawal
A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
research Vibrational Spectroscopic Investigation and Molecular Structure of a 5α-Reductase Inhibitor: Finasteride
Finasteride's molecular properties and active sites were identified using computational methods.
research Development of Microemulsions Containing Carthamus Tinctorius Extract for 5α-Reductase Inhibition
A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.
research The Efficacy of Ostrich Antibodies to Dihydrotestosterone and 5α-Reductase in the Restoration of Hair Growth
Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.
research The Skin Findings of Pregnant Women and Our Treatment Choices: A Turkish Experience Over a 5-Year Survey
Turkish pregnant women commonly experienced skin issues like itching and acne, and doctors mainly used topical treatments due to safety concerns during pregnancy.
research Comparison of the Efficacy and Safety of Topical 5% Minoxidil Solution Alone and in Combination with 0.05% Betamethasone Dipropionate Cream in the Treatment of Alopecia Areata
The combination of minoxidil and betamethasone is more effective for hair regrowth than minoxidil alone.
research Comparison of Microneedling With Platelet Rich Plasma Versus Minoxidil (5%) Plus Finasteride (0.1%) Topical Therapy in Androgenetic Alopecia: A Randomised Clinical Study
Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.
research In Vitro Evaluation of Skin Distribution and Human Dermal Papilla Cells Proliferation for Minoxidil 5% Topical Lotion Hydrogel
The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.
research Comparative Study Between Topical Methotrexate 1% Gel and Minoxidil 5% Gel in the Treatment of Localized Alopecia Areata
Minoxidil showed better improvement than methotrexate in treating localized alopecia areata.
research Correction to: Comparative Study to Evaluate Tolerability of Topical 5% Minoxidil Novel Formulation and Alcohol-Based Conventional Solutions in Treatment of Androgenetic Alopecia in Indian Men: Randomized Double-Blind Study
research Vibrational Spectroscopic Investigation and Molecular Structure of a 5α-Reductase Inhibitor: Finasteride
The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.
research Potential Synergistic Effects of Haedoksamul-Tang and Finasteride on 5α-Reductase Inhibition and Proliferation of Human Follicle Dermal Papilla Cells
HST and HST/F promote hair growth and may help treat alopecia.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Post-Finasteride Syndrome
research Faculty Opinions Recommendation of Minoxidil Dose Response Study in Female Pattern Hair Loss Patients Determined to Be Non-Responders to 5% Topical Minoxidil
60% of women who didn't respond to 5% minoxidil for hair loss showed significant improvement with a 15% minoxidil solution.
research Comparing the Effectiveness of Local Solution of Minoxidil and Caffeine 2.5% with Local Solution of Minoxidil 2.5% in Treatment of Androgenetic Alopecia
Minoxidil with caffeine works better for hair loss than minoxidil alone.
research Study on Genetic Polymorphisms of Androgen Receptor Gene and 5α-Reductase Genes of Han Men with Androgenetic Alopecia in Eastern China
research Clinical Expression and Morbidity of Systemic Lupus Erythematosus During a Post-Diagnostic 5-Year Follow-Up: A Male to Female Comparison
Gender affects the symptoms and severity of systemic lupus erythematosus.
research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients With Male Pattern Baldness
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia
Microneedling with platelet-rich plasma and minoxidil improves hair growth more than just minoxidil in men with hair loss.
research More About X-Linked Testicular Feminization of the Mouse as a Noninducible (is) Mutation of a Regulatory Locus: 5α-Androstan-3α-17β-Diol as the True Inducer of Kidney Alcohol Dehydrogenase and β-Glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.