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The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

The compound 4c effectively inhibits the enzyme linked to hair loss.

Compound 15a was effective in inhibiting 5α-reductase.

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Men taking 5-alpha reductase inhibitors for prostate issues may be less likely to experience severe COVID-19, but it doesn't prevent ICU admission or death.

Plumbago zeylanica extract helps hair growth and reduces a hair loss-related enzyme.

The herbal hair gel could be a safe hair growth treatment with minimal side effects.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.

Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Bitter melon extract may help prevent hair loss and can be used in cosmetic products.

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

β-sitosterol and brassicasterol may help treat hair loss.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Licorice extract helps hair growth and may treat hair loss.

Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.

Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.