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Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.

More research is needed to understand how testosterone is maintained in adult males.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Men who start losing hair at age 30 may have a lower risk of prostate cancer.

Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Compound 15a was effective in inhibiting 5α-reductase.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

5-Alpha-Reductase inhibitors might help slow down hair loss in Frontal Fibrosing Alopecia but are not a primary treatment and need more research.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Gene differences may affect baldness treatment response in Korean men.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.