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Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.

Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.

Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Finasteride doesn't affect sleep spindles in men.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Licorice extract helps hair growth and may treat hair loss.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.