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Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Finasteride is a safe and effective long-term treatment for prostate enlargement, reducing prostate volume and related symptoms.

Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.

The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.

Minoxidil is the only FDA-approved treatment for female hair loss, with other potential treatments needing more research for effectiveness.

Finasteride for hair loss in young men increases the risk of sexual dysfunction.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.