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A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Finasteride negatively affects fish reproduction and gonadal development.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride doesn't affect sleep spindles in men.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Finasteride effectively treats male hair loss, improving growth and density.

Finasteride doesn't harm bone density in older men with BPH.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Both drugs lower DHT levels, with GI198745 being more effective.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.