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The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

The new 5% minoxidil formulation without propylene glycol effectively promotes hair growth with fewer side effects and better user satisfaction.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

The cat had a rare condition linked to cancer, leading to its euthanasia.

Androgens and estrogens are crucial for insulin secretion in males.

A lotion with Centella asiatica extract reduced hair loss by 41% and increased hair strength without side effects.

A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.

7.5% DEET lotion is more effective and safe at repelling mosquitoes than rosemary, citronella, and lemongrass lotions.

Both 5% minoxidil solution and milky lotion effectively and safely treat male hair loss, with the lotion being a good alternative for those sensitive to certain ingredients.

A 5-year-old girl with McCune-Albright syndrome grew abnormal hair due to the drug tamoxifen.

IGFBP-5 likely plays a key role in goat hair growth.

Testosterone increases muscle mass regardless of DHT conversion blocking.

Taking 5-alpha reductase inhibitors might be linked to breast cancer in men.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

Topical 5% minoxidil is safe and effective for treating hair loss in Korean men.

Topical Valproic acid and 5% Minoxidil both significantly increase hair count in Female Pattern Hair Loss, with similar side effects.

Compound 4 is a promising treatment for hair loss with low toxicity.

Combining 5% spironolactone and 5% minoxidil is safe and more effective for treating hair loss.

A 5-mg dose of oral minoxidil slightly lowers blood pressure temporarily, especially in those with higher initial blood pressure.

Adding PRP to minoxidil improves hair growth in male pattern baldness.

Finasteride may help reduce opioid use.

New 5% minoxidil solution improves scalp hydration, reduces redness, and may be safer for sensitive users.

Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Minoxidil increases hair weight and count temporarily in men with hair loss.