Search
for
Sort by
Research
30-60 / 1000+ results![Expression of mRNA for androgen receptor, 5alpha-reductase and 17beta-hydroxysteroid dehydrogenase in human dermal papilla cells](/images/research/cfa8152f-fcc1-4596-8ef6-20532a6f28d3/small/28195.jpg)
research Expression of mRNA for androgen receptor, 5alpha-reductase and 17beta-hydroxysteroid dehydrogenase in human dermal papilla cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
![A Mouse Model of Androgenetic Alopecia](/images/research/8d0e5ba9-5d93-4d91-b1a8-f2b6d1ef2c9b/small/2954.jpg)
research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.
![5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence](/images/research/ec03129a-6496-4e9e-a072-f84349625090/small/20830.jpg)
research 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence
5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
![New Target for Minoxidil in the Treatment of Androgenetic Alopecia](/images/research/474bd822-58b8-4293-a97b-7f4b2e660a16/small/15701.jpg)
research New Target for Minoxidil in the Treatment of Androgenetic Alopecia
Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
![Androgen receptor: A promising therapeutic target in breast cancer](/images/research/d87f276d-7635-48af-852d-511a21db081c/small/17725.jpg)
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
![The Role of Histone Demethylases in Disease](/images/research/da4990a1-53a3-484e-84de-0d8be6dd5494/small/19892.jpg)
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
![Androgen Receptor Ligands: Agonists and Antagonists](/images/research/fa5bb319-d1d5-47c6-8b96-404f1f196490/small/13618.jpg)
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
![Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men](/images/research/3b5fe04f-9f3d-4560-ab28-44e5526d2bc5/small/18315.jpg)
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
![Expression of steroidogenic enzymes in human sebaceous glands](/images/research/ca574fcf-c40b-4c77-93f5-8910e3339e98/small/31133.jpg)
research Expression of steroidogenic enzymes in human sebaceous glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
![Potential targets in the discovery of new hair growth promoters for androgenic alopecia](/images/research/c04ea5fe-328f-40b5-8f56-0ce38fbf3e69/small/3464.jpg)
research Potential targets in the discovery of new hair growth promoters for androgenic alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
![Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia](/images/research/8d613c41-aef0-49d3-be22-32d350ba0074/small/4262.jpg)
research Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
![Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women](/images/research/fe399dd0-cd41-4109-b3b0-69032311536e/small/32635.jpg)
research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
![The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells](/images/research/1e23ee09-7f8b-476d-9937-7986628b97cc/small/18593.jpg)
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
![Minoxidil Use in Dermatology, Side Effects and Recent Patents](/images/research/d0a42951-e2dd-43a3-bfab-7395ee9b5521/small/3160.jpg)
research Minoxidil Use in Dermatology, Side Effects and Recent Patents
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
![Androgens/Androgen Receptor in the Management of Skin Diseases](/images/research/e88f3f96-57dc-422a-9978-20bb405ba9b2/small/15764.jpg)
research Androgens/Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
![β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress](/images/research/32d00083-92bb-466b-9c04-9c5de1433ae9/small/27061.jpg)
research β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress
NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.
![Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men](/images/research/bb64dad5-9932-49d2-82f1-e8ede280d423/small/12148.jpg)
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
![Basics of androgen synthesis and action](/images/research/34880441-f7d5-4a5e-be45-0b7b5f05fc8f/small/32706.jpg)
research Basics of androgen synthesis and action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
![Acne](/images/research/e3650fb1-08d1-4a02-a86f-25b17d96a2ef/small/26161.jpg)
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
![Prostaglandin D <sub>2</sub> Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia](/images/research/c02d0397-c3bb-420c-950f-472bed8f41ce/small/3146.jpg)
research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
![Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior](/images/research/b7e1f38f-0f40-4661-bafe-bf4798b8f0a0/small/18805.jpg)
research Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
![Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture](/images/research/fabd174c-bcb2-4336-935e-a0331c2fc108/small/33995.jpg)
research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
![A review of diagnosis and treatment of acne in adult female patients](/images/research/b08990d1-4e89-4c65-84c4-b0b81132db99/small/17916.jpg)
research A review of diagnosis and treatment of acne in adult female patients
Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
![Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters](/images/research/14310444-0063-4a30-bd41-1e0a5a49d1fe/small/18011.jpg)
research Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
![Acquired immunogenicity of DNA after modification with malondialdehyde in patients with alopecia areata](/images/research/b1931884-b7be-4902-8389-614b193b3a61/small/34635.jpg)
research Acquired immunogenicity of DNA after modification with malondialdehyde in patients with alopecia areata
Malondialdehyde-modified DNA may trigger an immune response in alopecia areata patients.
![Evaluation of antioxidant and oxidant status, including levels of Malondialdehyde (MDA) and Superoxide Dismutase (SOD), in the Indian population with alopecia areata](/images/research/4e1c9e0e-1a89-4f03-9f12-47018af5c577/small/36774.jpg)
research Evaluation of antioxidant and oxidant status, including levels of Malondialdehyde (MDA) and Superoxide Dismutase (SOD), in the Indian population with alopecia areata
Oxidative stress is important in causing alopecia areata.
research Ischemic modified albumin as a new biomarker in predicting of oxidative stress in alopecia areata
Ischemic modified albumin could be a new indicator of oxidative stress in people with alopecia areata.
research Pre-receptor regulation of the androgen receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.