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New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Long-term finasteride treatment reduces depression and brain issues in obese male rats.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Hair loss drugs may cause sexual issues and infertility in men.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Smaller finasteride particles increase effectiveness in treating hair loss.