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Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Compound 15a was effective in inhibiting 5α-reductase.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Testosterone's muscle-building effects do not require its conversion to DHT.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

Some herbs show promise as antiandrogenic agents.

New compounds may soon be tested to treat excessive hair growth in women.

Compounds from the plant Mammea siamensis may help treat hair loss.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

The herbal hair gel could be a safe hair growth treatment with minimal side effects.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Licorice extract helps hair growth and may treat hair loss.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Women also use 5α-reductase inhibitors, and their effects differ from men.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Dutasteride improved both hair loss and acne in two young men.

Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.