2 citations
,
December 2008 in “Journal of Chemical Crystallography” This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.
99 citations
,
September 2007 in “The American journal of pathology” This study found that organ-cultured human scalp hair follicles can mimic chemotherapy-induced damage in vivo and serve as a model to explore molecular targets and protective agents for hair follicle preservation.
19 citations
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September 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This study suggests that pretreatment with a PPAR-γ modulator may prevent damage to hair follicle stem cells caused by a chemotherapy metabolite, potentially offering a strategy to mitigate permanent chemotherapy-induced alopecia.
19 citations
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July 2015 in “Journal of Ginseng Research” In this study, Korean Red Ginseng showed protective effects against chemotherapy-induced premature hair follicle aging in an in vitro model by modulating specific cellular protein expressions.
18 citations
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August 2008 in “Journal of Investigative Dermatology” 17-β estradiol and prednisolone may speed up hair regrowth after chemotherapy.
April 2023 in “Journal of Investigative Dermatology” This study found that ALRN-6924 effectively protected human hair follicles from cyclophosphamide-induced damage in an ex vivo setting, suggesting it may reduce both acute and permanent chemotherapy-induced alopecia.
January 2015 in “프로그램북(구 초록집)” This study found that Korean Red Ginseng may protect against chemotherapy-induced alopecia by reducing hair follicle damage in a human hair follicle organ culture model.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the PPARγ modulator NAC-GED-0507-Levo may protect hair follicles from chemotherapy-induced damage, potentially offering a strategy to address irreversible hair loss in cancer patients.
8 citations
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June 1995 in “Helvetica Chimica Acta” This article outlines the synthesis of spiro[cyclohexane‐1,2′‐[2 H ]indene] derivatives similar to known steroid 5α‐reductase inhibitors, but it does not report experimental findings.
February 2025 in “Buletin Veteriner Udayana” This case study reports that a 4-month-old local male dog with scabiosis due to Sarcoptes scabiei infection improved after receiving a combination of ivermectin, antihistamines, supportive therapies, and sulfur shampoo for 28 days, with new hair growth observed by the 40th day.
3 citations
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January 2000 in “Current Medical Research and Opinion” This research reported that eflornithine HCl 13.9% cream generally has a favorable dermal safety profile for managing unwanted facial hair in women, though it can cause mild irritation under certain conditions.
1 citations
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July 2017 in “Microbial Cell Factories” This study found that supplementing soybean oil significantly increased the production of the cyclosporine A derivative [(4'-OH)MeLeu]4-CsA by 55.6%, offering potential enhancements for its clinical application.
January 2026 in “Neuroscience Applied” Hair cortisol levels decrease as children age, stabilizing around age 4.
January 2018 in “Digital Scholarship - UNLV (University of Nevada Reno)” This study found significantly higher hair cortisol concentrations in black children compared to white children aged 1-4 years, suggesting racial differences in cumulative stress as measured by hair cortisol.
2 citations
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January 2012 in “Hair therapy & transplantation” This study observed that DDAIP-HCl enhanced the permeation of minoxidil through human cadaver skin, suggesting potential for improved treatment efficacy in male pattern hair loss.
May 2021 in “Histochemistry and Cell Biology” This article highlights studies on cholesterol transporter proteins in hair cycles, epithelial-to-mesenchymal transition in cancer, ovarian hormone effects on cell polarity before implantation, and UV effects on rodent skin, without providing new clinical results.
October 2011 in “The American Journal of Gastroenterology” This study found that methadone use in HCV-infected male veterans was associated with a significant increase in the risk of advanced liver fibrosis.
5 citations
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January 2024 in “Crystals” This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.
1461 citations
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March 2004 in “Annals of oncology” This study found that in first-line treatment of metastatic breast cancer, pegylated liposomal doxorubicin (PLD) provided similar progression-free survival to doxorubicin with significantly less cardiotoxicity.
November 2018 in “DergiPark (Istanbul University)” This case report describes successful treatment of Malassezia overgrowth and resulting dermatitis in a Chinchilla cat using Terbinafine HCL and Omega fatty acid supplements, emphasizing Malassezia's potential as a marker for underlying diseases.
February 2024 in “Psychoneuroendocrinology” This study found no significant changes in hair steroid concentrations among preschoolers from before to after the COVID-19 pandemic onset, but noted that children from higher-income families showed a deregulation in stress markers, suggesting increased stress levels.
January 2024 in “Veterinary Science and Medicine Journal” In this case report, a 1.5-year-old Pomeranian named Beb with respiratory and skin issues was diagnosed with pneumonia and demodecosis; following a two-week treatment including antibiotics, ivermectin, and supportive care, Beb's symptoms resolved, and hair regrowth was observed.
34 citations
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April 2001 in “PubMed” This study found that eflornithine HCl 13.9% cream reduces unwanted facial hair growth in women, with effects seen in up to 60% of participants over 4-8 weeks, with mostly minor skin irritation reported.
3 citations
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July 2023 in “Biomolecules” This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.
85 citations
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January 2014 in “Hormone Research in Paediatrics” This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.
24 citations
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October 2018 in “Addiction Biology” This study found that alcohol dependence is associated with altered HPA axis functioning, with AD patients showing higher hair cortisol concentrations and reduced ACTH and cortisol levels, irrespective of childhood maltreatment history.
11 citations
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January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
6 citations
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July 2018 in “Steroids” This study found that testosterone significantly influenced the expression and function of certain ion transporters in the vas deferens, impacting fluid secretion and contributing to a suitable environment for male fertility.
1 citations
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July 2023 in “Psychoneuroendocrinology” This study found that hair cortisol concentration is consistently associated with salivary cortisol output throughout the day, making it a potential reliable biomarker of long-term cortisol secretion.
November 2024 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” In this study, researchers investigated the use of the Pulse Booster Drug Delivery Mesojectgun technology for non-invasive treatment of scalp conditions, finding improvements in hair volume, thickness, and reduction of hair loss in four participants with alopecia after applying specific active ingredients.