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This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.

PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.

This review discusses the potential of polydeoxyribonucleotide (PDRN) for various dermatological treatments and highlights its significant effects on wound healing, anti-aging, acne scars, and hair loss, but emphasizes the need for further clinical studies.

This study demonstrated that VD3 significantly enhanced the proliferation and differentiation of epidermal stem cells in a murine skin defect model, leading to improved wound healing, potentially through activation of the PI3K signaling pathway.

This study introduces a magnet-assisted fabrication strategy for creating complex 3D soft bioscaffolds, demonstrating its effectiveness by producing structures with overhangs and supporting biohybrid actuators, promising advancements in biomedical applications.

This study found that a new "bead-jet" printing system for mesenchymal stem cells in Matrigel beads improved skeletal muscle regeneration and skin healing in a high-density, sparse pattern.

This review article summarizes recent advancements in biomimetic scaffolds, highlighting their promise in tissue engineering and personalized medicine, particularly for skin and musculoskeletal system regeneration, while emphasizing the need for more extensive research to ensure their safety for human use.

This study describes a protocol for generating a fully functional 3D integumentary organ system from murine induced pluripotent stem cells, including the formation of hair follicles and sebaceous glands that function in vivo.

This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.

This study found that microporous electrospun scaffolds with a 70:30 collagen I to poly(ɛ-caprolactone) ratio significantly accelerated wound closure and dermal regeneration in full-thickness critical-sized skin defects.

In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.

This article describes a new T-Fast multi-implanter that potentially reduces operating costs and surgical time by implanting two follicular unit excision grafts simultaneously, which may encourage clinics to adopt this technique.

This study investigated how 2D and 3D cell culturing methods influence hair follicle morphogenesis, finding that 3D cultures responded more expectedly to minoxidil while 2D cultures reacted better to DHT treatment, challenging the assumption that 3D cultures are always superior.

The project developed and tested a method using plasma rich platelets to treat hair loss.

This study demonstrated that PRP treatment improved hair metrics in androgenetic alopecia, with the dermapen method proving more effective than the point-by-point technique for specific hair growth indicators.

This study identified novel isoforms of the PADI2 and PADI3 proteins, showing that PADI2β inhibits oligodendrocyte differentiation, possibly by opposing the effect of canonical PADI2, while PADI3β modulates the activity of PADI3α, suggesting new regulatory mechanisms of citrullination in tissue development.

This study analyzed trends in tissue expansion research and identified acellular dermal matrix's effect on breast reconstruction complications as a current key topic, with patient-activated controlled expansion as a potential future focus.

This study identified a gene transcript overexpressed in dermal papilla cells, showing strong similarity to a mouse gene associated with adipose tissue in bombesin receptor subtype-3-deficient mice.

This study found that combining optical clearing methods with light-sheet fluorescence microscopy allows detailed 3D visualization of normal and pathological human skin biopsies, revealing differences in epidermal thickness and volume.

This study suggests that KRTAP2-3 may serve as a novel biomarker to identify cells in the polyaneuploid cancer cell state, which is linked to therapy resistance and poor prognosis in prostate cancer.

This research reviews the roles of dermal papilla signaling in hair follicle development and suggests new genetic tools could advance bioengineering therapies for alopecia, but it reports no new results.

This study found that human peptidylarginine deiminase type III is the predominant isoform in hair follicles and may modulate structural proteins during hair and hair follicle formation.

This study found that intrauterine PRP infusion is a safe and effective treatment for patients with refractory thin endometrium and implantation failures, with the improvement primarily driven by the angiogenic cytokines in PRP.

This study found that a phosphodiesterase 3 inhibitor promoted hair growth in human dermal papilla cells and stimulated anagen induction in mice, suggesting potential as a treatment for alopecia.

PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.

This study found that combining Fractional CO2 laser with platelet-rich plasma led to better improvement in vitiligo treatment compared to platelet-rich plasma alone, based on patient satisfaction and lesion size reduction.

In this study, pantothenic acid at 20 μg/ml was observed to promote dermal papilla cell proliferation and migration, likely through up-regulation of ID3 and inhibition of Notch signaling.

This study evaluated the effectiveness of follicular units and growth factors derived from autologous platelet-rich plasma in improving hair growth and density in 23 male patients with pattern hair loss.

In this study, fibronectin coating on a low-adhesive substratum increased cell aggregation, growth, and motility, enhancing the formation of hair follicle dermal papilla spheroids.

This invention reports piperazine derivatives as potent inhibitors of type 3 17β-hydroxysteroid dehydrogenase, suggesting potential therapeutic applications in treating prostate cancer, acne, and androgenic alopecia.