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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Alcohol in teen years leads to more adult drinking, finasteride doesn't help.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Early NAS level changes affect alcohol consumption vulnerability.

Finasteride might affect memory by impacting cholinergic system.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Finasteride may increase depression by reducing brain cell growth.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.