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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

A new method accurately measures nine specific hormones in human blood.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Botanicals like green tea extract show potential for hair growth, but more research is needed.

Testosterone may slow down wound healing and increase inflammation.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Glioblastoma cells can make androgens, which might help the tumor grow.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.