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Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

DHT, a testosterone byproduct, causes male pattern baldness.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Botanicals like green tea extract show potential for hair growth, but more research is needed.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

Testosterone may slow down wound healing and increase inflammation.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Borneol Essential Oil could be a natural and safe acne treatment.

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Glioblastoma cells can make androgens, which might help the tumor grow.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.