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210-240 / 1000+ resultsresearch Ethosomes: An Exciting and Promising Alcoholic Carrier System for Treating Androgenic Alopecia
This chapter reviews ethosomes for targeted drug delivery to the scalp in androgenetic alopecia and reports no clinical results; the authors emphasize reducing systemic side effects.
research Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
research Ethosome as a potential transdermal drug delivery system
This review examines ethosomal structures and their mechanisms as skin delivery systems, outlining preparation methods and applications but presents no new experimental findings.
research Dermal drug delivery with ethosomes: therapeutic potential
This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.
research Extracellular vesicle as therapeutic agents in anti-aging: Mechanistic insights and future potential
research Protective effects of Ecklonia cava extract on the toxicity and oxidative stress induced by hair dye in in-vitro and in-vivo models
This study found that adding 7% Ecklonia cava extract to oxidative hair dyes significantly reduced their cytotoxicity and oxidative stress without affecting color performance.
research An alternative diagnostic method of eruptive vellus hair cysts: Report of a familial case with pruritus
This study suggests using a handheld dermatoscope may allow for simple and efficient differentiation of eruptive vellus hair cysts by detecting vellus hair shafts, as demonstrated in a familial case involving five women.
research Platelet Extracellular Vesicles Loaded Gelatine Hydrogels for Wound Care
This study demonstrated that gelatine-based hydrogel foams loaded with platelet extracellular vesicles (pEVs) promoted full wound closure in a chronic wound rat model within 14 days, suggesting potential for personalized treatment of chronic diabetic wounds.
research Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil:in vitroevaluation of drug permeation by infrared spectroscopy
PEVs effectively deliver minoxidil through skin.
research Equine Epidermis: A Source of Epithelial-Like Stem/Progenitor Cells with In Vitro and In Vivo Regenerative Capacities
This study found that treating skin wounds with a combination of epidermis-derived epithelial-like stem/progenitor cells and platelet-rich plasma improved tissue repair and increased vascularization and elastin content compared to platelet-rich plasma alone.
research Cepharanthine inhibits enterovirus entry by endolysosomal deacidification and exhibits protective activity in vivo
This study found that cepharanthine may be a promising treatment for enterovirus infections, as it offered full protection to mice against lethal EV71 challenges and reduced viral titers and pathology.
research Abstract P5-21-05: ERALOP study: Post adjuvant FEC - docetaxel chemotherapy for early breast cancer: Hair regrowth in the real life
This study found that persistent significant alopecia was a common side effect following FEC-docetaxel chemotherapy, with a 33.4% global incidence, highlighting the need for awareness and potential preventative measures like cooling caps during treatment.
research Improvement of androgenic alopecia by extracellular vesicles secreted from hyaluronic acid-stimulated induced mesenchymal stem cells
This study found that extracellular vesicles derived from hyaluronic acid-stimulated induced pluripotent stem cells significantly improved hair growth in a model of androgenetic alopecia in mice by enhancing Wnt/β-catenin signaling and regulating androgen receptor activity, showing comparable results to the commonly used treatment finasteride.
research Vitamin E promotes dermal papilla cell proliferation via the lncRNA2919/STAT1 axis to activate the Hedgehog signaling pathway
The study reports that vitamin E improves hair-follicle growth and dermal papilla cell proliferation in vitro by modulating the lncRNA2919/STAT1/SHH axis in Angora rabbits, enhancing cellular antioxidant capacity.
research Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin
This study developed an efficient method for isolating and enriching multipotent ovine hair follicle stem cells, which may aid in research on the ovine hair cycle and future wool production.
research New potential chemotherapy for ovarian cancer — Combined therapy with WP 631 and epothilone B
This review discusses the potential of combined therapy with WP 631 and epothilone B for ovarian cancer, but reports no new clinical results.
research Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms
This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.
research Secondary Amenorrhea and Clinical Hyperandrogenism in a 34-Year-Old Female: Polycystic Ovary Syndrome or Not?
This case study reported a 34-year-old woman presenting with secondary amenorrhea, hirsutism, and obesity showed elevated testosterone and anti-Müllerian hormone levels, leading to the exclusion of nonclassical congenital adrenal hyperplasia as a diagnosis.
research Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies
This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.
research Botanical Extract Coacillium for Management of Paediatric Atopic Dermatitis: A Case Report
research Heat-Killed Enterococcus faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice
This study found that heat-killed Enterococcus faecalis EF-2001 promoted hair regrowth in mice, likely by increasing the expression of growth factors and marker genes.
research In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers
This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
research Efficacy to hair growth with the combination of 5-aminolevulinic acid and iron.
research Early Recurrence of Eruptive Vellus Hair Cysts after Er
This study found that while Er:YAG laser therapy can initially improve the appearance of eruptive vellus hair cysts, it was ineffective in preventing early recurrences due to limitations in ablation depth.
research A guide to cost-effective emollient prescribing
This study highlighted the critical role emollients play in managing dry skin conditions and reported that prescribing suitable emollient therapy may reduce overall healthcare costs and the need for additional medications in UK primary care.
research A review on ethosomes promising as novel drug delivery systems
This study discusses ethosomes, which are lipid-based vesicular carriers that improve drug penetration into the skin due to their high ethanol content, highlighting their benefits in drug delivery despite stability issues like phospholipid oxidation and vesicle fusion during storage.
research Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial
In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.
research Injectable Thermosensitive Placental ECM –Copper Hydrogel With Endothelial Progenitor Cells for Pressure Ulcer Repair
This study found that a hydrogel made from human placenta-derived ECM, copper, and endothelial progenitor cells significantly enhanced pressure ulcer healing in a mouse model by improving wound closure and tissue regeneration.
research Transethosomes: A Comprehensive Review of Ultra-Deformable Vesicular Systems for Enhanced Transdermal Drug Delivery
Transethosomes improve drug delivery through the skin and show promise for treating various conditions.