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August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
45 citations,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
43 citations,
November 1992 in “International Journal of Dermatology” Minoxidil 2% effectively treats female hair loss, promoting growth and density.
42 citations,
June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
37 citations,
January 2011 in “Annals of Dermatology” ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.
34 citations,
June 2009 in “British journal of dermatology/British journal of dermatology, Supplement” Vitamin C derivative helps hair grow longer by making cells produce a growth factor through a specific cellular pathway.
33 citations,
February 2006 in “Journal of Dermatological Science” A long-acting Vitamin C derivative helps hair grow by stimulating cells and increasing growth factors.
32 citations,
March 2021 in “Journal of cosmetic dermatology (Print)” COVID-19 infection may trigger alopecia areata in some patients.
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May 2017 in “Lasers in medical science” Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.
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April 1999 in “Expert Opinion on Investigational Drugs” Finasteride effectively treats male hair loss, improving growth and density.
29 citations,
April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
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March 2010 in “Journal of Endocrinological Investigation” Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.
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November 2014 in “Current Diabetes Reports” Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.
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October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
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August 2019 in “Journal of The American Academy of Dermatology” Using 2% tofacitinib cream with narrowband ultraviolet B improved facial vitiligo by 70% in patients who didn't respond to previous treatments, with no side effects reported.
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July 1994 in “Archives of Dermatology” A man's skin condition, pemphigus vulgaris, came back after he was treated with interleukin 2 for cancer.
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June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
22 citations,
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
22 citations,
August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
22 citations,
July 2006 in “Journal of Dermatological Science” Vitamin C derivative increases versican in cells, potentially aiding hair growth.
22 citations,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
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July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
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December 2005 in “Journal of Investigative Dermatology Symposium Proceedings” IFN-γ and IL-2 are important for T cell activation in hair loss in mice.
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May 2016 in “Clinical, cosmetic and investigational dermatology” FGF-2&D/P nanoparticles can help treat hair loss.
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January 2019 in “Journal of cancer” The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
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October 2013 in “F1000Research” A 2-year-old boy grew excessive hair after using minoxidil for hair loss, but it improved when the treatment stopped.
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September 2019 in “International Journal of Women's Dermatology” Type 2 diabetes may increase the risk of severe hair loss in African American women.
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August 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” A3B5 can reduce skin pigmentation and slow melanoma growth.
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May 1987 in “Fundamental and applied toxicology” SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.
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September 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Interleukin levels are higher in alopecia areata patients but don't predict disease severity or duration.