research The Experimental Studies of YangHyulEum Gami-Bang Extracts on the Hair Growth Effect
YangHyulEum Gami-Bang extract may help treat hair loss.
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research Genetics of Polycystic Ovary Syndrome
PCOS has a strong genetic basis, but more research is needed to fully understand it.
research Werner's Syndrome: Incidental Finding During Pregnancy
A pregnant woman with Werner's syndrome died during childbirth, but her baby survived and did not have the syndrome.
research Recent Progress in Prostaglandin F2a Ethanolamide (Prostamide F2a) Research and Therapeutics
Bimatoprost treats glaucoma and promotes hair growth, with potential for more medical uses.
research Hair-Growth Promoting Effect of Bimatoprost
Bimatoprost effectively promotes hair growth.
research Dermatology
Minoxidil can help hair growth but may not always look cosmetically good.
research The Role of Moracin M in Promoting Hair Growth: Insights into Mechanisms of WNT/β-Catenin Pathway Activation and Angiogenesis Enhancement in Human Dermal Papilla Cells
Moracin M, a compound from the Moraceae family, has been shown to significantly enhance hair growth by promoting cell proliferation and angiogenesis in human dermal papilla cells (hDPCs). The study found that Moracin M activates the Wnt/β-catenin signaling pathway, leading to increased levels of growth factors such as VEGF, FGF2, KGF, HGF, and MYC, similar to the effects of minoxidil. It also enhances cell migration in human umbilical vein endothelial cells (HUVECs) without cytotoxicity at concentrations up to 50 µM. Additionally, Moracin M increases protein and mRNA levels of VEGF, FGF2, and KGF under inflammatory conditions and stimulates MMP-2 and MMP-9 expression, contributing to wound healing. These results suggest that Moracin M could be a promising alternative to current hair growth treatments.
research Human Regulatory Gamma Delta T Lymphocytes as Novel Autoimmunity-Protective Cells: Lessons from Alopecia Areata
γδTregs may help treat autoimmune diseases like alopecia areata by promoting hair regrowth and reducing immune attacks.
research Scalp Condition Improvement With Botanical Extracts Possessing Chemical And Physical Antioxidant Activity
The study investigates the potential of botanical extracts to improve scalp conditions by reducing oxidative stress, which affects hair and scalp health. Using both chemical and biological antioxidant mechanisms, 10 botanical extracts were tested for their ability to combat reactive oxygen species (ROS). The study employed ORAC testing, a Nrf-2 cell assay, and a 3D human keratinocyte model to evaluate antioxidant activity. A 4-week consumer study with 56 participants using a leave-on treatment containing a botanical extract showed a reduction in oxidized lipids on the scalp. The results indicate that incorporating botanicals with antioxidant properties into hair and scalp care products can enhance scalp health.
research Screening and Expression Validation of Key Proteins for Secondary Hair Follicle Growth in Cashmere Goats Based on iTRAQ Quantitative Proteomics Technology
FKBP10 and FBN2 are key proteins for hair growth in cashmere goats.
research Novel Investigational Drugs for Alopecia Areata and Future Perspectives
JAK inhibitors are safe and effective for treating moderate-to-severe alopecia areata.
research The Effects of Negative Pressure Therapy on Hair Growth of Mouse Models
Negative pressure therapy increases hair growth in mice.
research Network Pharmacology Analysis and Experimental Evaluations of YH Complex on Androgenetic Alopecia by Regulating the Androgenic-Apoptotic Axis
The YH complex, made from certain plant extracts, effectively promotes hair regrowth and could be a potential treatment for hair loss.
research JAK Inhibitor Baricitinib in the Treatment of Oral Lichen Planus: A Case Report
Baricitinib may effectively treat oral lichen planus.
research Tribuloside Acts on the PDE/cAMP/PKA Pathway to Enhance Melanogenesis, Melanocyte Dendricity and Melanosome Transport
Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
research Comorbidities In Patients With Central Centrifugal Cicatricial Alopecia: A Case-Control Study
Patients with central centrifugal cicatricial alopecia often have higher rates of metabolic, autoimmune, and atopic conditions, as well as anxiety and depression.
research Scarring Alopecia Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
Cancer treatment drugs can cause permanent hair loss by damaging hair follicle stem cells, but a specific inhibitor might reverse this effect.
research Dermatophytosis Caused by Trichophyton Spp. in a Local Kitten
The kitten's skin condition improved significantly after 4 weeks of treatment.
research Otitis Externa Due to Complication of Otodectes Cynotis, Bacteria, and Malassezia sp. Accompanied by Scabiosis in Domestic Cat
The cat's ear and skin issues improved significantly after 10 days of treatment.
research Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders
Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.
research Advances In The Mechanism And New Therapies Of Alopecia Areata
New treatments targeting the JAK signaling pathway, especially JAK inhibitors, show promise for alopecia areata.
research Dermatological Perspectives on Pressure Alopecias: A Call for Awareness
Increased awareness and research are needed to prevent hair loss from cosmetic procedures.
research Life of the B10 Mouse: A View from the Hair Follicles and Tissue Stem Cells
Mice skin matures by day 200, leading to aging signs like curved hair follicles and white hairs due to changes in skin stem cells.
research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
research Skin Manifestations and Biophysical Changes Following Weight Reduction Induced by Bariatric Surgery: A 2-Year Prospective Study
Bariatric surgery improved many skin conditions in obese patients but caused hair loss in some and decreased facial oil and skin elasticity.
research Hormonal Profile of Androgenetic Alopecia in Adolescents and Its Association With Metabolic Dysfunction: Single Center Retrospective Study
Adolescents with hair loss show different hormone levels by sex and often have related metabolic issues.
research Topical Metformin as a Novel Therapy for Alopecia Areata Due to Its Immunologic Effects
Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
research Multilayered Gel-Spotting Device for In Vitro Reconstruction of Hair Follicle-Like Microstructure
The new method can create hair follicle-like structures but not complete hair with roots and shafts, needing more improvement.
research Investigations of 13 Genes in Non-Cicatricial Alopecia
DNA analysis can help tailor alopecia treatment.
research Treatment Of Alopecia Universalis In A Child With Down Syndrome
Topical treatments helped a child with Down syndrome and severe hair loss regrow most of his hair.