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Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Too much androgen can cause hair loss; finasteride may help.

Testosterone may slow down wound healing and increase inflammation.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Sebocytes play a key role in controlling androgen levels in human skin.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Androgens and other hormones affect hair growth and skin conditions like acne.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.