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Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Use antiandrogens and other treatments for hair loss.

New cytokine-targeted therapies show promise for treating alopecia areata.

Genetic mutations can affect female sexual development, requiring personalized medical care.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Fat cells in the skin help start healing and form important repair cells after injury.