Search

everythinglearnresearchcommunity

for

Search:↓

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Sebocytes play a key role in controlling androgen levels in human skin.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

DHT, a testosterone byproduct, causes male pattern baldness.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.