37 citations,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
34 citations,
December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
33 citations,
November 2008 in “European Journal of Pharmaceutical Sciences” St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
32 citations,
February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
31 citations,
March 2017 in “Journal of The American Academy of Dermatology” Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.
31 citations,
April 1999 in “Dermatologic Clinics” Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
30 citations,
August 1983 in “Pediatric Clinics of North America” Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.
29 citations,
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26 citations,
September 2012 in “Epilepsy & Behavior” Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
22 citations,
January 2001 in “Chemical & Pharmaceutical Bulletin” Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
14 citations,
April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
13 citations,
December 2010 in “Archives of Dermatology” Minoxidil use can cause trichostasis spinulosa in long-term hair loss patients.
12 citations,
May 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Activating TRPV3 channels stops hair growth by killing hair follicle cells.
11 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
10 citations,
August 2020 in “Journal of Bioscience and Bioengineering” Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.
10 citations,
January 2014 in “Chemical and Pharmaceutical Bulletin” Ethanol pretreatment affects drug penetration through skin and hair follicles.
10 citations,
January 2013 in “Journal of Cutaneous and Aesthetic Surgery” Narrower donor strips and special closure techniques in hair transplants lead to smaller scars and happier patients.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
9 citations,
January 1989 in “Sen'i Gakkaishi” Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.
7 citations,
October 2019 in “Case reports in endocrinology” A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
7 citations,
June 2004 in “Dermatologic Surgery” A new hair transplant method combines individual and group follicles for better results and efficiency.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
5 citations,
November 2014 in “Journal of Pharmaceutical Sciences” 5 citations,
May 2004 in “Dermatologic Surgery” A hair restoration technique was introduced that mixes different types of hair groupings to reduce procedure time, limit damage, and potentially increase hair density, suggesting more hair can be transplanted than previously thought.
3 citations,
July 2021 in “Drug Testing and Analysis” 5α-reductase inhibitors can interfere with doping tests by masking banned substances.
3 citations,
December 2020 in “Scientific reports” Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
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February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
2 citations,
April 1999 in “Dermatologic Clinics” The paper concludes that creating a natural-looking hairline in hair restoration is important for facial aesthetics and involves careful planning and realistic expectations.
2 citations,
October 1997 in “Dermatologic Clinics” The document concludes that advancements in hair restoration surgery have led to more natural results and patient satisfaction, with hope for future improvements in treatment.
1 citations,
February 2021 in “Journal of Cosmetic Dermatology” Using a 30°-sapphire blade at a lower angle causes the least injury in hair transplants.