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Glossary Hair Loss Gene

genetic variations linked to increased risk of hair loss

The term "Hair Loss Gene" refers to specific genetic variations that are associated with an increased risk of hair loss conditions, such as androgenetic alopecia (commonly known as male or female pattern baldness). One well-known gene linked to hair loss is the AR gene, which affects androgen receptor activity and can influence hair follicle sensitivity to hormones like dihydrotestosterone (DHT). Understanding these genetic factors can help in diagnosing and developing targeted treatments for hair loss.

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Research

5 / 1000+ results

research Safety and efficacy analysis of liposomal insulin-like growth factor-1 in a fluid gel formulation for hair-loss treatment in a hamster model

18 citations , August 2012 in “Clinical and Experimental Dermatology”

This study concluded that a 3% IGF-1 liposomal gel improved hair thickness and growth in hamsters without inducing significant hepatotoxicity or myelotoxicity, suggesting its potential as a safe hair-loss treatment.

research Efficacy and tolerability assessment of a polynucleotide‐based gel for improvement of pattern hair loss Running title: A polynucleotide‐based gel for improvement of pattern hair loss

October 2023 in “Research Square (Research Square)”

This study demonstrated that polynucleotide gel injections effectively reduced hair shedding and increased hair thickness in both men and women with androgenetic alopecia, while maintaining a high safety profile and patient satisfaction.

research Comparitive Study of Various Brands of Synthetic Hair Gels and Herbal Hair Gels

July 2021 in “Clinical Case Reports and Clinical Study”

This article discusses the formulation and potential benefits of herbal hair gels, highlighting their moisturizing properties and fewer side effects compared to marketed synthetic alternatives, but reports no experimental results.

research Herbal Hair Gel Formulation having 5α-Reductase Inhibitory Activity and its Standardization by HPTLC

4 citations , January 2016 in “Journal of analytical & bioanalytical techniques”

This study evaluated a hair growth gel with Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum extracts, demonstrating consistent homogeneity, 5 α-reductase inhibitory activity, and no skin irritation.

research Formulation and Evalaution of Flaxseeds Hair Gel

June 2024 in “International Journal for Research in Applied Science and Engineering Technology”

This study aimed to formulate and evaluate a herbal hair gel using flax seed and aloe vera for promoting hair development and combating dandruff, finding that one formulation maintained long-term stability and antifungal efficacy.

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Community Join

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community Surprise Hair Loss Breakthrough: A Sugar Gel Sparks Robust Regrowth

129 upvotes 11 months ago

A sugar gel is claimed to spark hair regrowth, but users express skepticism, noting that minoxidil and finasteride remain the most effective treatments. Many users joke about frequent "breakthroughs" that work on rats but not humans, and some mention the potential of PP405 as a future treatment.

community Surprise Hair Loss Breakthrough: A Sugar Gel Triggers Robust Regrowth

445 upvotes 1 year ago

A sugar gel was claimed to trigger hair regrowth, but users reported no results and potential cancer risks. The discussion included comparisons to minoxidil and skepticism about the effectiveness of the sugar treatment.

community A Surprise Hair Loss Breakthrough: Sugar Gel Triggers Robust Regrowth : ScienceAlert

254 upvotes 1 year ago

A sugar gel has been found to aid hair regrowth, similar to minoxidil, and may improve blood supply to hair follicles. Some users report success with homemade versions, though side effects like dizziness have been noted.

community Is hairloss from using tretinoin cream/gel temporary?

10 upvotes 2 years ago

Tretinoin is not commonly linked to hair loss and can enhance the effects of Minoxidil. Users recommend starting with lower doses and gradually increasing to avoid scalp irritation.

community Groundbreaking sugar gel might be a miracle hair loss solution for men and women

in Technology 125 upvotes 1 year ago

A sugar gel called 2-deoxy-D-ribose (2dDR) shows potential for promoting hair regrowth by increasing blood supply to hair follicles, similar to Minoxidil, but its effectiveness in humans is unproven. It may benefit those who don't tolerate Minoxidil, but it is not a replacement for treatments like Finasteride or RU58841.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.
Did you know PP405 peptides can help protect your follicles from DHT? PP405 is not a peptide and does not block DHT: it is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier, aimed at waking dormant follicles. Its registered Phase 2 trial (NCT06393452) measured safety and tolerability in 78 adults with pattern hair loss; it is not approved and not for sale.

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Platelet-Rich Plasma

Are Platelet results permanent, or does hair loss return once treatment stops? Hair loss typically returns after stopping PRP treatment, as effects are not permanent.

learn Vitamin B12

How can you tell if your hair loss is related to low Vitamin B12 levels? Hair loss may indicate low Vitamin B12 if accompanied by fatigue and anemia symptoms.

learn Hair Transplant

What is shock loss after a hair transplant? Shock loss is temporary hair shedding after a transplant, usually resolving in a few months.

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

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Clinics

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Experts

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