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GlossaryU2HR gene

regulates hair growth and can cause hair loss when mutated

The U2HR gene is not a standard term in genetics. However, it is often associated with a specific region within the U2HR (U2 Hairless Region) of the human genome that is involved in hair growth regulation. Mutations or alterations in this region can lead to conditions like alopecia, where individuals experience hair loss.

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research Marie Unna Hereditary Hypotrichosis: Identification of a U2HR Mutation in the Family from the Original 1925 Report

14 citations , April 2011 in “Journal of the American Academy of Dermatology”

Researchers found a gene mutation responsible for a rare hair loss condition.

research Marie Unna Hereditary Hypotrichosis: A Turkish Family with Loss of Eyebrows and a U2HR Mutation

11 citations , September 2010 in “American Journal of Medical Genetics - Part A”

A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.

research Identification of a Novel Heterozygous Mutation in the First Japanese Case of Marie Unna Hereditary Hypotrichosis

6 citations , January 2013 in “The Journal of Dermatology”

Researchers found a new genetic mutation causing a rare hair loss condition in the first Japanese child studied.

research Two Females With Hair Loss

July 2019 in “Journal der Deutschen Dermatologischen Gesellschaft”

A mother and daughter have a rare genetic hair loss disorder with no effective treatment.

research Clinical Course of the First Japanese Family with Marie Unna Hereditary Hypotrichosis: A Follow-Up Report

May 2018 in “European Journal of Dermatology”

The first Japanese family with Marie Unna hereditary hypotrichosis showed hair condition improvement in a child and highlighted the risk of misdiagnosis.

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