Search
for

    Glossary U2HR Mutation

    genetic alteration affecting hair growth regulation, potentially causing alopecia

    The U2HR mutation refers to a specific genetic alteration in the U2HR (U2 Hairless Repressor) gene, which is involved in the regulation of hair growth. This mutation can disrupt normal hair follicle function, potentially leading to conditions like alopecia, where hair loss occurs. For professionals, it's important to note that the U2HR gene plays a role in the signaling pathways that control hair follicle cycling and differentiation.

    Related Terms

    Research 10 of 22

    1. Marie Unna hereditary hypotrichosis: Identification of a U2HR mutation in the family from the original 1925 report Journal of the American Academy of Dermatology · 2011 · 14 citations
    2. Marie Unna hereditary hypotrichosis: A Turkish family with loss of eyebrows and a <i>U2HR</i> mutation American Journal of Medical Genetics - Part A · 2010 · 11 citations
    3. Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis Nature Genetics · 2009 · 181 citations
    4. Identification of a novel heterozygous mutation in the first Japanese case of Marie Unna hereditary hypotrichosis The Journal of Dermatology · 2013 · 6 citations
    5. Marie-unna hereditary hypotrichosis International Journal of Trichology · 2014 · 4 citations
    6. Odd-Looking Hair and Progressive Alopecia in Mother and Son JAMA Dermatology · 2014
    7. Two females with hair loss Journal der Deutschen Dermatologischen Gesellschaft · 2019
    8. Clinical course of the first Japanese family with Marie Unna hereditary hypotrichosis: a follow-up report European Journal of Dermatology · 2018
    9. Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families Human Genetics · 2010 · 40 citations
    10. A TP63 Mutation Causes Prominent Alopecia with Mild Ectodermal Dysplasia 2020 · 2 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →