Search
for

    Glossary U2HR protein

    truncated protein inhibiting hair growth gene, affecting follicles

    The U2HR protein is a truncated form of the U2HR (U2 Hairless Repressor) gene product, which plays a role in hair growth regulation. It acts as an inhibitor of the hairless (HR) gene, which is crucial for hair follicle cycling and maintenance. By interfering with the HR gene's function, the U2HR protein can potentially lead to conditions like alopecia, where hair growth is disrupted.

    Related Terms

    Research 10 of 22

    1. Marie Unna hereditary hypotrichosis: A Turkish family with loss of eyebrows and a <i>U2HR</i> mutation American Journal of Medical Genetics - Part A · 2010 · 11 citations
    2. Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis Nature Genetics · 2009 · 181 citations
    3. Two females with hair loss Journal der Deutschen Dermatologischen Gesellschaft · 2019
    4. Odd-Looking Hair and Progressive Alopecia in Mother and Son JAMA Dermatology · 2014
    5. A TP63 Mutation Causes Prominent Alopecia with Mild Ectodermal Dysplasia 2020 · 2 citations
    6. Inherited Disorders of the Hair Elsevier eBooks · 2013 · 2 citations
    7. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    8. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    9. Disease causing homozygous variants in the human hairless gene International Journal of Dermatology · 2015 · 7 citations
    10. Hair loss and its management in children Expert Review of Dermatology · 2011 · 5 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →