Connexin 43 Expression in the Testes During Postnatal Development of Finasteride-Treated Male Rat Offspring

    February 2017 in “ Archives of Medical Science ”
    Agnieszka Kolasa, Kamila Misiakiewicz-Has, Irena Baranowska-Bosiacka … Barbara Wiszniewska
    Studysummary This study found that finasteride treatment in male rats may lead to changes in connexin 43 expression in the testes of their offspring, potentially affecting spermatogenesis.
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    Research cited in this study 17

    1. Androgen Levels and Apoptosis in the Testis During Postnatal Development of Finasteride-Treated Male Rat Offspring Folia Histochemica Et Cytobiologica · 2015
    2. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
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    5. DHT Deficiency Perturbs the Integrity of the Rat Seminiferous Epithelium by Disrupting Tight and Adherens Junctions Folia Histochemica et Cytobiologica · 2011
    6. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    7. Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage Fertility and Sterility · 2011
    8. Finasteride-Associated Male Infertility Fertility and Sterility · 2010
    9. The Expression of Inducible Nitric Oxide Synthase (iNOS) in the Testis and Epididymis of Rats with a Dihydrotestosterone (DHT) Deficiency Cellular & Molecular Biology Letters · 2009
    10. Expression of E-SOD, GPX5 mRNAs and Immunoexpression of Cu/ZnSOD in Epididymal Epithelial Cells of Finasteride-Treated Rats Andrologia · 2008
    11. Propecia-Induced Spermatogenic Failure: A Report of Two Cases Fertility and Sterility · 2007
    12. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 2007
    13. Spermatozoa and Chronic Treatment with Finasteride: A TEM and FISH Study Archives of Andrology · 2007
    14. Natural Variability and the Influence of Concurrent Control Values on the Detection and Interpretation of Low-Dose or Weak Endocrine Toxicities Environmental Health Perspectives · 2004
    15. Long-Term Multinational Experience with Finasteride 1 mg in the Treatment of Men with Androgenetic Alopecia PubMed · 2002
    16. Steroid 5α-Reductases and 3α-Hydroxysteroid Dehydrogenases: Key Enzymes in Androgen Metabolism Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism · 2001
    17. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992

    Related research 1

    1. Androgen Levels and Apoptosis in the Testis During Postnatal Development of Finasteride-Treated Male Rat Offspring Folia Histochemica Et Cytobiologica · 2015