The Potential Role of Fibroblast-Derived Multi-Peptide Factors in Activation of Growth Factors and Beta-Catenin in Hair Follicle Cells

    Jung-Hye Shin, Young-Yoon Lee, Kyung Min Kim … Young Lee
    Studysummary This study suggests that dermal fibroblast-conditioned medium containing multi-peptide factors may stimulate hair growth by enhancing growth factor expression and β-catenin regulation in hair follicle cells.
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    Research cited in this study 10

    1. Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration During Wound Healing Journal of Investigative Dermatology · 2021
    2. More Is Not Always Better in Hair Growth Factors: Epidermal Growth Factor Involved in Alopecia Areata Pathogenesis International Journal of Trichology · 2020
    3. Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia Skin appendage disorders · 2017
    4. Epidermal β-Catenin Activation Remodels the Dermis via Paracrine Signaling to Distinct Fibroblast Lineages Nature Communications · 2016
    5. Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia Experimental Dermatology · 2014
    6. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    7. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    8. Hematological And Hepatic Effects Of Vascular Epidermal Growth Factor (VEGF) Used To Stimulate Hair Growth In An Animal Model BMC dermatology · 2013
    9. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    10. Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993

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