The Potential Role of Exosomes in Aesthetic Plastic Surgery: A Review of Current Literature

    June 2023 in “ Plastic and Reconstructive Surgery – Global Open ”
    Yonson Ku, Hafsa Omer Sulaiman, Spencer R. Anderson, Ali R. Abtahi
    Studysummary This review found that exosome use in aesthetic plastic surgery shows promise in areas like skin rejuvenation and hair restoration, with laboratory studies indicating enhanced outcomes, but clinical evidence remains largely anecdotal, and no exosome-based products have FDA approval.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 15

    1. Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway Frontiers in Bioengineering and Biotechnology · 2021
    2. Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion Nutrients · 2021
    3. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    4. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    5. Current Advances in Stem Cell-Based Therapies for Hair Regeneration European Journal of Pharmacology · 2020
    6. Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/β-Catenin Pathway in Dermal Papilla Cells Biomolecules & Therapeutics · 2020
    7. Exosome for Hair Regeneration: From Bench to Bedside Journal of the American Academy of Dermatology · 2019
    8. A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth ACS nano · 2019
    9. Exosomes Derived from Human Dermal Papilla Cells Promote Hair Growth in Cultured Human Hair Follicles and Augment the Hair-Inductive Capacity of Cultured Dermal Papilla Spheres Experimental Dermatology · 2019
    10. Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation International journal of biological sciences · 2019
    11. Problems and Solutions for Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Review Aesthetic Plastic Surgery · 2018
    12. Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
    13. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017
    14. Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation Nature cell biology · 2017
    15. Embryonic Hair Follicle Fate Change by Augmented Beta-Catenin Through Shh and Bmp Signaling Development · 2009