Features of Skinfold Thickness in Ukrainian Men With Alopecia Areata

December 2025 in “ Reports of Morphology ”

M. A. M. Shakatira, S. V. Dmytrenko, S. V. Prokopenko, I. A. Golubovsky, O. O. Gonchar, V. F. Zverkhovska, T. M. Kyselova

alopecia areata skinfold thickness body fat distribution pathogenetic mechanisms

Studysummary This study found that young adult Ukrainian men with alopecia areata had significantly different skinfold thickness at several body sites compared to healthy peers, suggesting unique patterns of fat distribution associated with the disease.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study examined skinfold thickness (SFT) in 81 young adult Ukrainian men with alopecia areata compared to 82 healthy controls. Results showed significantly higher SFT in men with alopecia areata on the posterior and anterior surfaces of the arm, forearm, chest, and flank, but lower SFT on the thigh and under the inferior angle of the scapula. These variations in SFT suggest a "subpathological" constitutional type associated with alopecia areata, indicating potential changes in body fat distribution linked to the disease. The findings could enhance understanding of the disease's pathogenetic mechanisms and aid in early diagnosis and personalized therapy.

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research Global Burden of Alopecia Areata and Associated Diseases: A Trend Analysis From 1990 to 2021

February 2025 in “PubMed”

This study found that although the global incidence of alopecia areata has risen since 1990, age-standardized rates have slightly decreased, with significant comorbidity associations varying by region.

research Alopecia Areata Is Associated With An Increased Risk For Prediabetes And Obesity: A Nationwide Case-Control Study

January 2025 in “Journal of Personalized Medicine”

This study found that patients with alopecia areata had a higher prevalence of prediabetes and obesity compared to healthy controls, suggesting the importance of regular screening and early management of these conditions in this population to mitigate associated health risks.

research Association of Androgenetic Alopecia with Metabolic Syndrome

October 2024 in “Journal of College of Physicians And Surgeons Pakistan”

In this study, researchers observed an association between androgenetic alopecia and metabolic syndrome, suggesting potential benefits in screening individuals with this type of hair loss for metabolic issues to prevent further health complications.

research Non-Cicatricial Alopecia and Its Association with Anthropometric Measurements and Nutritional Laboratory Markers

7 citations , May 2024 in “Life”

This study found no significant laboratory differences between Caucasian adults with non-cicatricial alopecia and healthy controls, but reported that affected individuals were significantly younger, suggesting that lifestyle and diet might contribute to early hair loss risk.

research Trends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population

75 citations , March 2023 in “JAMA Dermatology”

This study reported that the prevalence of alopecia areata in the US slightly increased from 0.199% to 0.222% between 2016 and 2019, with higher rates observed in women and adults.

research A Study of Correlation of Alopecia Areata and Metabolic Syndrome in Northwest Indian Population

5 citations , March 2023 in “International Journal of Trichology”

This study reported a similar prevalence of metabolic syndrome in patients with alopecia areata as in healthy controls, with no statistically significant differences observed.

research Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels

11 citations , July 2022 in “Frontiers in immunology”

This study reports that the global age-standardized incidence and disability-adjusted life-year rates of alopecia areata decreased from 1990 to 2019, with the highest increases in incidence seen in some low SDI regions and countries like Kuwait and South Sudan.

research Alopecia Areata: Current Understanding and Management

11 citations , January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft”

This review discusses current and emerging therapies for alopecia areata, highlights the challenges in managing this chronic disease, and emphasizes the importance of addressing its psychosocial impacts; it reports no new clinical results.

research Systematic Review and Meta-Analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia

3 citations , December 2021 in “Acta dermato-venereologica”

This meta-analysis found that patients with androgenetic alopecia had a significantly higher prevalence of metabolic syndrome and poorer metabolic profiles compared to controls, especially among females, those with early onset, and individuals of African ethnicity.

research The Epidemiology of Alopecia Areata: A Population-Based Cohort Study in UK Primary Care

117 citations , July 2021 in “British Journal of Dermatology”

This study reports that the incidence of alopecia areata is 0.26 per 1000 person-years in the UK, with higher rates among Asian ethnic groups, socially deprived populations, and urban residents.

research Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Lifestyle Habits

13 citations , February 2020 in “Clinical, Cosmetic and Investigational Dermatology”

In this study, men with androgenetic alopecia had lower BMI and waist-to-hip ratios than controls, but no significant association with hypertension or other lifestyle factors was observed.

research The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study

10 citations , January 2019 in “Indian Journal of Dermatology”

This study found that male patients with early-onset androgenetic alopecia were associated with metabolic syndrome, but not insulin resistance, compared to age-matched controls.

research Study of Prevalence of Metabolic Syndrome in Androgenetic Alopecia

October 2018 in “International Journal of Research in Dermatology”

In this study, androgenetic alopecia patients had a significantly higher prevalence of metabolic syndrome and related metabolic disorders compared to those without the condition.

research Alopecia and the Metabolic Syndrome

30 citations , September 2017 in “Clinics in Dermatology”

This review explores the relationship between androgenetic alopecia and metabolic syndrome, suggesting an association that supports considering cardiovascular risk assessments in patients with this type of hair loss.

research Metabolic Syndrome in Androgenic Alopecia

16 citations , January 2016 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that men with early-onset androgenic alopecia had a higher prevalence of metabolic syndrome compared to controls without the condition.

research Epidemiology and Burden of Alopecia Areata: A Systematic Review

144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.