Improvement of Cell Proliferation and Antioxidant Activity of Silymarin in Hair Follicles Dermal Papillae Isolated from the Human Scalp: Comparison with Vitamin C Effects
January 2020
in “
International Journal of Trichology
”
TLDR Silymarin improves hair follicle health better than vitamin C by boosting cell growth and reducing oxidative stress.
The study examined the effects of silymarin and vitamin C on dermal papilla cells (DPCs) from human scalp hair follicles, involving 5 participants. Silymarin, at concentrations of 50 and 100 μmol, was found to enhance cell proliferation and exhibit antioxidant properties, suggesting protective effects against oxidative stress in hair follicles. While both silymarin and vitamin C increased antioxidant activity, vitamin C was more effective in reducing reactive oxygen species and enhancing total antioxidant capacity. The study concluded that silymarin could be beneficial for promoting hair growth and protecting hair follicles, but further in vivo research was needed to confirm its efficacy.
