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Glossary Milk Thistle

flowering herb used for liver health and antioxidant properties

Milk Thistle, also known as Silybum marianum, is a flowering herb that has been used for centuries for its medicinal properties, particularly in supporting liver health. It contains an active compound called silymarin, which is believed to have antioxidant, antiviral, and anti-inflammatory effects.

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research Flavonoid Silibinin Increases Hair-Inductive Property Via Akt and Wnt/��-Catenin Signaling Activation in 3-Dimensional-Spheroid Cultured Human Dermal Papilla Cells

29 citations , February 2019 in “Journal of Microbiology and Biotechnology”

This study found that silibinin may promote hair growth by increasing proliferation and activating the AKT and Wnt/β-catenin signaling pathways in 3D cultured human dermal papilla spheroids.

research Improvement of cell proliferation and antioxidant activity of silymarin in hair follicles dermal papillae isolated from the human scalp: Comparison with vitamin C effects

8 citations , January 2020 in “International Journal of Trichology”

Silymarin improves hair follicle health better than vitamin C by boosting cell growth and reducing oxidative stress.

Improving Ovulation Rate in Women with Polycystic Ovary Syndrome Using Silymarin

research Improving an Ovulation Rate in Women with Polycystic Ovary Syndrome by Using Silymarin

3 citations , March 2017 in “Iraqi Journal of Pharmaceutical Sciences”

This study found that combining silymarin with metformin improved hormone levels and ovulation rate in patients with polycystic ovary syndrome more effectively than either treatment alone.

research Advances in Extraction Technologies of Silybum marianum L. and Its Role in Protecting Against Skin Damage

1 citations , September 2025 in “Cosmetics”

This study's literature synthesis suggests that silymarin, derived from milk thistle, may offer protective benefits for the skin, including defense against UV damage and support for wound healing, though further clinical studies are needed.

Evaluation of Efficacy of Silybum Marianum Flower Extract on Mitigating Hair Loss In Vitro and In Vivo

research Evaluation of efficacy of Silybum marianum flower extract on the mitigating hair loss in vitro and in vivo

1 citations , September 2023 in “Journal of cosmetic dermatology”

This study suggests that Silybum marianum flower extract may promote hair growth and reduce hair loss by increasing proliferation and VEGF production in dermal papilla cells and suppressing cell senescence.

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community Minoxidil (5% Rogaine foam) 0.5 Dutasteride

16 upvotes 9 months ago

A user shared their hair loss experience and treatment routine, which includes using Minoxidil (5% Rogaine foam) and Dutasteride 0.5, along with various supplements and natural oils. They reported positive results and emphasized the importance of liver health and thyroid function, despite skepticism from others about the effectiveness of supplements.

community Noticing hair loss after eating certain foods

3 months ago

The user experiences hair loss and scalp reactions after eating certain non-organic foods, leading them to adopt an all-organic diet which has stabilized their hair condition. Suggestions include using liver-supporting herbs and considering gut health issues like histamine sensitivity.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Mark Normand talks about finasteride experience

in Finasteride/Dutasteride 826 upvotes 3 years ago

The conversation is about hair loss and the use of finasteride as a treatment. Some users share their positive experiences with finasteride, while others mention side effects they have experienced.

community Please can someone explain all the Dutasteride horror stories on here

in Finasteride/Dutasteride 114 upvotes 1 year ago

Switching from finasteride to dutasteride for hair loss yields mixed results, with some users experiencing improvements and others facing worsening conditions or side effects like shedding. Patience is advised as dutasteride may take longer to show results, and combining treatments is suggested by some users.

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