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    Glossary Milk Thistle

    flowering herb used for liver health and antioxidant properties

    Milk Thistle, also known as Silybum marianum, is a flowering herb that has been used for centuries for its medicinal properties, particularly in supporting liver health. It contains an active compound called silymarin, which is believed to have antioxidant, antiviral, and anti-inflammatory effects.

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    1. Flavonoid Silibinin Increases Hair-Inductive Property Via Akt and Wnt/��-Catenin Signaling Activation in 3-Dimensional-Spheroid Cultured Human Dermal Papilla Cells Journal of Microbiology and Biotechnology · 2019 · 29 citations
    2. Improvement of cell proliferation and antioxidant activity of silymarin in hair follicles dermal papillae isolated from the human scalp: Comparison with vitamin C effects International Journal of Trichology · 2020 · 8 citations
    3. Improving an Ovulation Rate in Women with Polycystic Ovary Syndrome by Using Silymarin Iraqi Journal of Pharmaceutical Sciences · 2017 · 3 citations
    4. Advances in Extraction Technologies of Silybum marianum L. and Its Role in Protecting Against Skin Damage Cosmetics · 2025 · 1 citations
    5. Evaluation of efficacy of <i>Silybum marianum</i> flower extract on the mitigating hair loss in vitro and in vivo Journal of cosmetic dermatology · 2023 · 1 citations
    6. Formulation and Characterization of a Polyherbal Sunscreen Containing Camellia sinensis, Vitis vinifera, and Silybum marianum Extracts Pharmacognosy Research · 2025 · 1 citations
    7. Exploring the therapeutic potential of naturally occurring taxifolin, a dietary flavonoid: an updated comprehensive review Frontiers in Pharmacology · 2026
    8. Interest of an anti-hair loss serum containing Silybum marianum extract, manganese pyrrolidone carboxylic acid (PCA), and a Lespedeza capitata extract in the management of post-cancer treatment alopecia: an international real-world study EJC Skin Cancer · 2026
    9. Dichotomy JAAPA · 2025
    10. New Plant Extracts Exert Complementary Anti‐Hair Loss Properties in Human In Vitro and Ex Vivo Models Journal of Cosmetic Dermatology · 2024
    11. Preparation and in vitro evaluation of protective effects of Silibinin‐loaded polymeric micelles on human hair against UV‐B radiation Journal of cosmetic dermatology · 2024
    12. ESDR586 - Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase 2022
    13. 10-Year-Old Female with an Irregularly Shaped Patch of Hair Loss Clinical Cases in Dermatology · 2022
    14. 301 Association between Hair Proliferation and Flavonoid Silibinin in Human Dermal Papilla Cells Journal of Investigative Dermatology · 2019
    15. P122 : Flavonoid silibinin induces hair growth in 3-dimensional cultured human dermal papilla cells 프로그램북(구 초록집) · 2019
    16. A one-year exploratory randomized, controlled, multicentric pilot study evaluating the efficacy and tolerance of an anti-hair loss serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract following hair transplantation in men with androgenic alopecia Frontiers in Medicine · 2026
    17. Supplementary file 1_A one-year exploratory randomized, controlled, multicentric pilot study evaluating the efficacy and tolerance of an anti-hair loss serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract following hair transplantation in men with androgenic alopecia.docx Figshare · 2026
    18. Health Benefits, Antioxidant Activity, and Sensory Attributes of Selected Cold-Pressed Oils Molecules · 2023
    19. 586 Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase Journal of Investigative Dermatology · 2022
    20. 721 Efficacy of silybum marianum extract, manganese PCA and lespedeza capitata extract on hair growth and anchorage in human dermal papilla cells 2022
    21. Supplements That May Counteract Side Effects from Conventional Cancer Therapies 2006
    22. Plant cell culture as emerging technology for production of active cosmetic ingredients Engineering in Life Sciences · 2018 · 67 citations
    23. Nutrition Strategy and Life Style in Polycystic Ovary Syndrome—Narrative Review Nutrients · 2021 · 49 citations
    24. Novel cosmeceuticals from plants—An industry guided review Journal of Applied Research on Medicinal and Aromatic Plants · 2017 · 39 citations
    25. Therapeutic Applications of Nanoemulsion Based Drug Delivery Systems: A Review of Patents in Last Two Decades Recent Patents on Drug Delivery & Formulation · 2011 · 39 citations
    26. Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor Bioinformation · 2012 · 16 citations
    27. Optimization and Characterization of <i>Cuscuta reflexa </i>Extract Loaded Phytosomes by the Box-Behnken Design to Improve the Oral Bioavailability Journal of Oleo Science · 2022 · 15 citations
    28. Androgen Receptor in Human Health: A Potential Therapeutic Target Current Drug Targets · 2012 · 12 citations
    29. Recent Trends and Future Prospects of Phytosomes: A Concise Review Indian Journal of Pharmaceutical Sciences · 2024 · 11 citations
    30. Herbal Treatment for Dermatologic Disorders Oxidative stress and disease · 2011 · 9 citations