Serum Nuclear Factor E-2-Related Factor 2 in Female Pattern Hair Loss

February 2022 in “ Journal of Cosmetic Dermatology ”

OA Bakry, Soha Sobhy, M Essam El Deen, Iman Seleit

Female Pattern Hair Loss FPHL total oxidant capacity TOC oxidative stress index OSI nuclear factor erythroid-2-related factor 2 NRF2 total antioxidant capacity TAC systemic oxidative stress NRF2 activators oxidative stress antioxidants

Studysummary This study suggests that systemic oxidative stress in female pattern hair loss may be related to NRF2 deficiency, and NRF2 activators might assist in treatment.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

15 / 15 results

research The Role of Prostaglandins in Androgenetic Alopecia

4 citations , February 2021 in “International Journal of Dermatology”

This study found that increased levels of PGD2 and prostacyclin and decreased levels of PGE2 and PGF2α were associated with baldness in androgenetic alopecia, suggesting potential targets for treatment.

research Female Pattern Hair Loss: A Comprehensive Review

15 citations , July 2020 in “Dermatologic Therapy”

This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.

research The Impact of Oxidative Stress in Androgenic Alopecia in Women

7 citations , January 2020 in “Postepy Dermatologii I Alergologii”

Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.

research Female Androgenetic Alopecia: An Update on Diagnosis and Management

43 citations , November 2019 in “American Journal of Clinical Dermatology”

This review discusses female androgenetic alopecia, highlighting its diagnostic challenges and management strategies, but it reports no new results.

research Review of Quality of Life Studies in Women with Alopecia

58 citations , January 2018 in “International Journal of Women's Dermatology”

This review discusses the psychological impact of alopecia on women and reports no new clinical findings, highlighting the effect on self-esteem and quality of life.

research The Role of Oxidative Stress in Early-Onset Androgenetic Alopecia

13 citations , December 2016 in “Journal of Cosmetic Dermatology”

This study found increased oxidative stress in younger male patients with early-onset androgenetic alopecia compared to healthy peers, suggesting a potential role for antioxidants in their treatment.

research Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition

58 citations , October 2016 in “Journal of Investigative Dermatology”

This study found that activating Nrf2 in human hair follicles significantly reduced oxidative stress, lipid peroxidation, and protected against hair growth inhibition, suggesting a protective role for Nrf2 against redox insult in this context.

research Apoptosis in Follicles of Individuals with Female Pattern Hair Loss Is Associated with Perifollicular Microinflammation

30 citations , May 2016 in “International Journal of Cosmetic Science”

This study found that apoptosis was more prevalent in hair follicles of women with female pattern hair loss, particularly in miniaturized follicles, and was associated with follicular inflammation.

research Female Pattern Hair Loss: A Clinical and Pathophysiological Review

91 citations , August 2015 in “Anais Brasileiros De Dermatologia”

This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.

research The Female Pattern Hair Loss: Review of Etiopathogenesis and Diagnosis

35 citations , January 2014 in “BioMed Research International”

This review examines the epidemiology, pathogenesis, clinical manifestations, and diagnosis of female pattern hair loss and reports no new results.

research Male Androgenetic Alopecia

1 citations , January 2012 in “Human health handbooks”

This article reviews androgenetic alopecia and its genetic and hormonal influences, treatment options like minoxidil and finasteride, and its potential associations with other health conditions, reporting no new clinical results.

research Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome

54 citations , February 2010 in “British Journal of Dermatology”

This case report describes a patient with complete androgen insensitivity syndrome experiencing female pattern hair loss, suggesting that factors beyond direct androgen action may contribute to this condition in women.

research Dermoscopy in Female Androgenic Alopecia: Method Standardization and Diagnostic Criteria

129 citations , January 2009 in “International Journal of Trichology”

This study found that trichoscopy criteria can distinguish female androgenic alopecia from chronic telogen effluvium, with specific features achieving 98% diagnostic specificity.

research Female Pattern Hair Loss

226 citations , September 2001 in “Journal of The American Academy of Dermatology”

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations , September 1977 in “British Journal of Dermatology”

This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.