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GlossaryOxidative Stress

imbalance between free radicals and antioxidants causing cellular damage

Oxidative stress refers to an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants (molecules that neutralize free radicals) in the body. This imbalance can lead to cellular damage, also known as oxidative damage or oxidative injury, and is implicated in various conditions, including aging, cancer, and hair loss disorders like alopecia.

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research Oxidative Stress in Alopecia Areata: A Case-Control Study

62 citations, July 2013 in “American Journal of Clinical Dermatology”

Alopecia areata patients have higher oxidative stress and lower antioxidant levels.

research Association of Oxidative Stress in Mild Patchy Alopecia Areata: A Case-Control Study

October 2023 in “Research Square (Research Square)”

Oxidative stress is linked to mild patchy alopecia areata.

research The Role of Reactive Oxygen Species in the Pathogenesis of Alopecia Areata: A Systematic Review and Meta-Analysis

January 2025 in “Skin Pharmacology and Physiology”

Oxidative stress contributes to alopecia areata, suggesting antioxidant treatments might help.

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community A New Therapeutic Channel to Come Soon: Hair Follicle Sugar Metabolism and Aldose Reductase

in Research/Science 130 upvotes 3 years ago

Hair loss therapies focusing on hair follicle sugar metabolism and aldose reductase. Potential treatments include magnesium supplements, avoiding high glycemic index foods, and antioxidants.

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