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natural substance from Neem tree with medicinal and pesticidal properties
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a topical anti-androgen with less systemic involvement
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highly targeted anti-androgen that might have minimal systemic effects
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research Chronic Exposure With 5-Alpha Reductase Inhibitor Ameliorates Anxiety and Depression-Like Behaviors by Reducing Systemic Oxidative Stress in D-Galactose-Induced Aging Male Rats
Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
research Finasteride Effectively Attenuates the Impairments of Left Ventricular Function and Cardiac Sympathovagal Balance in Both Aging and Obese Male Rats via Reducing Systemic Oxidative Stress
Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Serum Nuclear Factor E-2-Related Factor 2 in Female Pattern Hair Loss
Women with pattern hair loss may have more stress in their bodies due to a lack of NRF2, a protein. Eating healthy and losing weight could help reduce this stress and improve hair loss. NRF2 boosters might also help treat this type of hair loss.
research Chronic Exposure of 5-Alpha Reductase Inhibitor in Young Male Rats Induces Metabolic Disturbance and Depressive-Like Behaviors
Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.
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5 / 1000+ resultscommunity NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress
NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.
community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications
The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
community 7 day break from Fin in order to donate blood?
A user needs to stop finasteride for 7 days to donate blood due to haemochromatosis. They are concerned if this break will affect their hair loss progress after 6 weeks of use.
community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.