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    Pathogenetic Rationale for the Use of Exosomes Derived from Salmon Tissue in Patients with Androgenetic Alopecia: A Prospective Uncontrolled Observational Study

    June 2026 in “ Russian Journal of Skin and Venereal Diseases ”
    Olga Olisova, Vera Smolyannikova, Karim Karray, Anfisa Lepekhova
    Studysummary This study evaluated salmon-derived exosomes combined with microneedling as a treatment for androgenetic alopecia, reporting significant improvements in hair density, follicular health, and scalp microenvironment, with no serious adverse events observed in the 20 patients after 12 weeks.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 13

    1. Exosomes And Hair Regeneration: A Systematic Review Of Clinical Evidence Across Alopecia Types And Exosome Sources Clinical Cosmetic and Investigational Dermatology · 2025
    2. Evaluation of the Effectiveness of Exosome Application in Patients with Androgenetic Alopecia: Case Series Russian Journal of Skin and Venereal Diseases · 2025
    3. Platelet-Rich Plasma-Derived Exosomes Stimulate Hair Follicle Growth Through Activation of the Wnt/β-Catenin Signaling Pathway Regenerative Therapy · 2025
    4. The Roles of Exosomes in Regulating Hair Follicle Growth Clinical Cosmetic and Investigational Dermatology · 2024
    5. Androgenetic Alopecia: A Review Nigerian Postgraduate Medical Journal · 2024
    6. Modern Aspects of External Application and Prospects of Using the Secretome of Mesenchymal Stem Cells (Review) Drug development & registration · 2024
    7. Diagnosis and Differential Diagnosis of Tertiary Androgenetic Alopecia With Severe Alopecia Areata Based on High-Resolution MRI Skin Research and Technology · 2023
    8. Cell Therapy for Androgenetic Alopecia: Elixir or Trick? Stem cell reviews and reports · 2023
    9. Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway International Journal of Molecular Sciences · 2023
    10. Hair Regrowth Treatment Efficacy and Resistance in Androgenetic Alopecia: A Systematic Review and Continuous Bayesian Network Meta-Analysis Frontiers in Medicine · 2023
    11. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    12. Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
    13. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015