Retinoic Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells

    June 2025 in “ Biomolecules ”
    Yu Zhang, Xuefei Zhao, Shuqi Li … Wei Zhang
    Studysummary In this study, researchers found that activating RORA in hair follicle stem cells reduced the expression of cytoskeleton-related genes, affecting cell migration and adhesion, which may aid in understanding hair follicle development and potentially inform alopecia treatments.
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    Research cited in this study 25

    1. The Retinoic Acid-Related Orphan Receptor Alpha May Be Highly Involved in the Regulation of Seasonal Hair Molting International Journal of Molecular Sciences · 2025
    2. Melatonin-Mediated Circadian Rhythm Signaling Exhibits Bidirectional Regulatory Effects on the State of Hair Follicle Stem Cells Biomolecules · 2025
    3. Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3 Animals · 2024
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